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Early fault detection of induced draft (ID) fans is very important to improve the reliability by providing predictive maintenance and reducing unscheduled shutdowns. This study proposed an early fault detection method for ID fans based on MSET with informative memory matrix selection. Firstly, to obtain an informative memory matrix, the discrete particle swarm optimization (DPSO) was utilized to search samples with large condition information. An accurate MSET model was then developed based on the memory matrix to produce predictions of t