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The biosynthesis of some compatible solutes and antioxidant compounds were inhibited. In addition, exposure to Fe-based NPs tentatively shut down some energy consuming pathways, such as photorespiration, alanine metabolism, branch chain amino acid biosynthesis. The trade-off of energy consuming pathways might be alternative explanation for the enhanced photosynthesis. The results of this study exhibited the promising potential for Fe-based NPs to be used in nano-enabled agriculture to promote plant growth.Debris flow is a typical natura