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First Line Treatment For ADHD in Adults Certain people suffering from ADHD find that medications help to manage their symptoms. like methylphenidate or amphetamine help by enhancing brain activity in areas that control attention and behavior. Other medications, such as the nonstimulant drug atomoxetine, and some antidepressants work differently, but they are effective. Patients who are taking medication should visit their GP regularly to check for the body's reactions and adjust dosages. Medication For