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candidates for application in the food and pharmaceutical industries and facilitated identification of further probiotics. Current guidelines recommend treatment of metabolic acidosis in chronic kidney disease (CKD) with Na -based alkali but base-producing fruits and vegetables (F+V) might yield more and better health outcomes, making the intervention cost-effective. In this post hoc analysis of a clinical trial we randomized 108 macroalbuminuric, nondiabetic CKD stage 3 participants with metabolic acidosis to receive F+V (n=36) calculat