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S. crispa ethanolic extract exhibited maximum antibacterial activity with an inhibition zone of 19.66 ± 0.88 mm against Escherichia coli compared to other bacterial strains. From these results, it could be assessed that S. crispa is a promising source of new antibacterial and antioxidant agents.Antiproliferative, antioxidant, and antibacterial activities were determined for 14 extracts obtained with a mixture of chloroform-methanol (11) from the mycelial cultures of 14 wild strains of the genus Ganoderma collected in the central-south pa