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98 (0.84-1.15), respectively, in men, respectively, and 0.90 (0.65-0.98), 0.61 (0.50-0.76), 0.46 (0.36-0.58), and 0.92 (0.81-1.04), respectively, in women, after full adjustment of confounding variables. Metformin use in an elderly population with DM reduced dementia risk in a dose-response manner. Metformin use in an elderly population with DM reduced dementia risk in a dose-response manner. To investigate the frequency of foot sudomotor dysfunction determined by the electrochemical skin conductance test (ESC) and its inde

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