https://r406inhibitor.com/?p=2730preview=true
Minimal expression of ALG9 and MEG3 predicted bad prognosis of AML customers. The altered degree of ALG9 was found matching into the drug-resistant phenotype and sphere development of AML cells. MiR-155 was overexpressed in M5/MDR patients and ADR-resistant AML cells, as well as inversely correlated to ALG9 expression. MEG3 was an immediate target of miR-155 and could sponge miR-155 in AML cells. MEG3 interacted with miR-155 to regulate ALG9 expression, which reversed the effects of ALG9 legislation on proliferation and drug resistance