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Skeletal undesirable events in early childhood cancer malignancy children: A grownup Life after Childhood Cancers inside Scandinavia cohort study. Malignant gliomas (MG) are among the most prevalent and lethal primary intrinsic brain tumors. Although radiotherapy (RT) is the most effective nonsurgical therapy, recurrence is universal. Dysregulated DNA damage response pathway (DDR) signaling, rampant genomic instability, and radio-resistance are among the hallmarks of MGs, with curr