https://www.selleckchem.com/pr....oducts/BI6727-Volase
BACKGROUND The orexin system regulates various functions, including sleep/wake cycles, feeding, and cognition. Orexin A and orexin B are endogenous neuropeptides for both orexin 1 (OX1) and orexin 2 (OX2) receptors. Orexin A has a potent agonistic activity for both the receptors and is known to increase locomotor activity in rats. However, it has not been elucidated how each receptor contributes to orexin A-induced hyperlocomotion. METHODS We examined the effects of an OX1 receptor antagonist, SB 334867, and an OX2 receptorant
Like
Comment
Share
