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Threshold values were observed at 158 mg/dl for all-cause mortality and 190 mg/dl as to cardiovascular mortality. Below the threshold, every 10 mg/dl increment in non-HDL-C attributed to relatively low all-cause mortality significantly (HR = 0.94, 95% CI 0.92-0.96). Above the threshold, non-HDL-C has significant positive associations with both all-cause (HR = 1.03, 95% CI 1.01-1.05) and cardiovascular mortality (HR = 1.09, 95% CI 1.05-1.14). For subgroups analysis, similar results were found among participants age less then 65 years old