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47, p less then 0.001). [Formula see text] was also significantly correlated with self-reported pain intensity (r = 0.44, p less then 0.001) and applied pain intensity (r = 0.43, p less then 0.001). Our results indicate that [Formula see text] is positively correlated with pain-related brain activity and subjective pain intensity. This study may thus represent a basis for adopting peripheral arterial stiffness as an objective pain evaluation metric.Unsupervised clustering models have been widely used for multimetric phenotyping of co
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