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ancer and could compensate for the limitations of the current screening methods for detection of CRC and advanced adenomas.Skeletal muscle wasting and weakness caused by cancer and its treatments (known as "cachexia" drastically impair quality of life and worsen survival outcomes in cancer patients. There are currently no approved treatments for cachexia. Hence, further investigation into the causes of cachexia induced by cancer and chemotherapy is warranted. Here, we sought to investigate skeletal muscle wasting, weakness and loss of