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What Happens If ADHD is Left Untreated in Adults? Untreated ADHD can lead to a range of problems for adults. This includes issues with relationships, work, and mental health. Adults with untreated ADHD often have low self-esteem and a pessimistic outlook on the world. They may feel like they are failing at work and at home. Lack of Focus Having trouble staying focused at times is normal and is commonplace, especially after a tiring day at school or at work. If you notice that your ab