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During the discovery of ColoRectal Cancer (CRC), 20% to 30% of patients have synchronous liver metastases. Ten to 30% of patients have non-evidence of Liver Metasteses (LM) following preoperative imaging such as Contrast-Enhanced Ultrasound (CE-US), multi-slice Contrast-Enhanced Computed Tomography (CE-CT), Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI), and Positron Emission Tomography-Computed Tomography (PET-CT). Today, IntraOperative UltraSound (IOUS) in open surgery and Laparoscopic UltraSound (LUS) in laparoscopic or robot

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