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The CB state, however, is metastable at low CS due to a thermodynamic energy barrier. The metastable CB wetting state becomes more stable on the SH microtextures with greater ϕ and r, in agreement with our experimental observations. Finally, we generalize this surface-energy analysis to provide useful designs of surface parameters for a DDAB-laden surfactant droplet on the SH surface with a stable and robust CB state.Due to their role in many important signaling pathways, phosphatidylinositol 5-phosphate 4-kinases (PI5P4Ks) are attract