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The current treatment of venous disease is focused on reflux elimination in main venous trunks, especially in the saphenous vein. However, a high recurrence rate, independent of the method of treatment, suggests that the reason of low effectiveness may be due to a strategy focused on symptoms, without considering their origin. The aim of study was the comparison of retrospective data from 535 women with venous disease, either after treatment ( = 183) or not treated before ( = 352). The analysis concerned clinical symptoms and the result