https://www.selleckchem.com/B-Raf.html
The intestinal capillary pathway is the most common way to absorb oral drugs, but for drugs with poor solubility and permeability and high first-pass metabolism, this pathway is very inefficient. Although intestinal lymphatic transport of lipophilic drugs or prodrugs is a promising strategy to improve the oral delivery efficiency of these drugs. The prodrug strategy for modifying compounds with Log P 5 to promote intestinal lymphatic transport is a common approach. However, transport of poor liposoluble compounds (Log P less then through