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Level III-retrospective cohort study. Level III-retrospective cohort study. Whether to preserve or sacrifice the intercostobrachial nerves (ICBN) is a controversial issue. In this trial, we aim to assess the effects of preservation of the ICBN during axillary dissection for patients with breast cancer in terms of pain score immediately postoperatively and several hours later, need for simple analgesia and narcotics, numbness and arm swelling. This is a single-institution, single-surgeon randomized controlled trial where a sample of 48 pat