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915 [1.311, 6.480]), prior open-heart surgery (2.820 [1.215, 6.544] and chronic obstructive pulmonary disease (2.506 [1.099, 5.714]) increased the risk of death. T he level of post-interventional mitral regurgitation had no relevant impact on survival. We conclude that after SMR and failed TMVR, reclipping is an appropriate treatment option for symptomatic patients. For PMR patients, surgery must be favored over a ReClip procedure. However, patients with atrial fibrillation, prior open-heart surgery and chronic obstructive pulmonary dise