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What Happens If ADHD is Left Untreated in Adults? Adults suffering from ADHD are susceptible to a variety of issues if the condition is not treated. These include problems with relationships, work, and mental health. Adults with untreated ADHD typically have low self-esteem, and have a negative outlook on the world. This can make them feel like failures both at work and at home. Lack of Focus It is normal to experience difficulty focusing from time to time, especially after a busy day at w