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Treatment For ADHD Psychosocial therapy is the primary ing. The medications contain stimulants such as methylphenidate, amphetamine and atomoxetine. They may also be nonstimulants, like clonidine and guanfacine. Patients who have active issues with substance abuse are not advised to take stimulant medication. However, those in stable remission can take them into consideration. Combination therapy using antidepressants particularly SSRIs, is an alternative option. S