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499 and 0.187; 95% confidence intervals 0.255-0.977 and 0.039-0.895). Furthermore, there were no differences in toxicities between the two groups. Belotecan was not inferior to topotecan in terms of overall response for recurrent ovarian cancer. NCT01630018. NCT01630018.An amendment to this paper has been published and can be accessed via a link at the top of the paper.Extrinsic black dental staining is an external dental discoloration of bacterial origin, considered a special form of dental plaque. Currently, there is no definitive