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Perioperative shivering (POS) is a common complication in patients undergoing spinal anaesthesia. The present study investigated the efficacy of 5-HT receptor antagonists in preventing POS following spinal anaesthesia. Systematic review and meta-analysis. Pubmed, Embase, the Web of Science and Cochrane Library were searched from database establishment on 31 July 2019. Randomised controlled trials that reported the effects of 5-HT receptor antagonists in the prevention of POS in patients after spinal anaesthesia. Two reviewers independen