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Finding the Best ADHD Medication For Adults Many adult ADHD treatment plans are based on medications. Finding the right medication dosage and medication is not always easy. Stimulants: These medicines can be used to treat both hyperactivity as well as inattention. They work by increasing the levels of chemicals that send messages between nerve cell. They are usually taken several times a day and start working within less than an hour. Stimulants Most doctors start with stimulants to treat ADHD. These drugs work by increasing activity in sp