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IMPLICATIONS Our study revealed a novel positive feedback loop LHFPL3-AS1/miR-580-3p/STAT3 in melanoma, which might contribute to finding potential therapeutic targets for melanoma.Multiple human polyomaviruses (HPyV) can infect the skin, but only Merkel cell polyomavirus (MCPyV) has been implicated in the development of a cancer, Merkel cell carcinoma (MCC). While expression of HPyV6, HPyV7, and MCPyV small T antigens (sT), all induced a senescence-associated secretory phenotype (SASP), MCPyV sT uniquely activated noncanonical NF-κB (ncN

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As pet owners, we strive to provide the best for our furry companions while also being mindful of our planet. This balance can sometimes feel challenging, particularly when it comes to choosing products that are both effective and environmentally friendly. In recent years, eco-friendly food dispensers have emerged as a popular option for pet parents looking to feed their pets sustainably. These innovative feeders not only nourish our beloved animals but do so in a way that