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Variomes is publicly available at https//candy.hesge.ch/Variomes. Source code is freely available at https//github.com/variomes/sibtm-variomes. SynVar is publicly available at https//goldorak.hesge.ch/synvar. Supplementary data are available at Bioinformatics online. Supplementary data are available at Bioinformatics online.Improvement of photosynthetic traits in crops to increase yield potential and crop resilience has recently become a major breeding target. Synthetic biology and genetic technologies offer unparalleled opportunities to