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Accurately diagnosing schizophrenia is still challenging due to the lack of validated biomarkers. Here, we aimed to investigate whether radiomic features in bilateral hippocampal subfields from magnetic resonance images (MRIs) can differentiate patients with schizophrenia from healthy controls (HCs). A total of 152 participants with MRI (86 schizophrenia and 66 HCs) were allocated to training (n=106) and test (n=46) sets. Radiomic features (n=642) from the bilateral hippocampal subfields processed with automatic segmentation techniques we