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(1) Background All deaths that occurred in a hospital of Southern Italy ("San Giuseppe Moscati" Hospital of Avellino) with medium jurisdiction (up to 425,000 citizens approximately) in the period from 9 March to 4 May 2020 were analyzed. The primary endpoint of the study was to analyze the causes of death in the period study. Secondary endpoints included (1) the assessment of overall mortality in the emergency period compared with the same period of the past years (2018-2019) in the jurisdiction area; (2) the assessment of the amounts