https://www.selleckchem.com/pr....oducts/BAY-73-4506.h
However, agonists of the eNOS/cGMP/PKG pathway reduced FBXW7 mRNA levels. FBXW7 overexpression suppressed primordial follicle activation and prevented the eNOS/cGMP/PKG pathway from activating primordial follicles and stabilizing mTOR protein. These findings demonstrate that the eNOS/cGMP/PKG pathway activates primordial follicles by suppressing FBXW7-induced ubiquitination of mTOR in mice.Drugs or compounds have been shown to promote longevity in various approaches. We used Drosophila to explore novel natural compounds can be appli
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