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Natural ADHD Medication Alternatives There are a variety of supplements and natural remedies that claim to treat ADHD. These treatments aren't controlled by the FDA and could cause side effects or interact with other medications. Pycnogenol, a plant extract, has proven promising to ease ADHD symptoms in some studies. It is believed that it improves cognitive function and decreases restlessness. Nootropics Many people suffering from ADHD who have been diagnosed have found that holistic treatments,