https://csg452agonist.com/eval....uation-regarding-use
To spot the amino acid substitutions which are involving version of avian-origin H7N7 virus to animals, version associated with the H7N7 virus was performed by serial lung-to-lung passageway in mice. Genomic evaluation of this mouse-adapted virus unveiled amino acid changes in the PB2 (E525G, M645I, and D701N), NP (I475V), HA(D103N), and NA(K142E) proteins. The modified H7N7 virus was even more virulent in mice compared to the wild-type virus. Our outcomes suggest that continued surveillance of po