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The %N3 increased in the first half-sleep and the first sleep cycle. PAH was relatively common in healthy young participants. Since PAH occurred in a state with a high prevalence of %N3, the first sleep cycle, or the first half-sleep, we suggest that PAH may be affected by the sleep homeostasis process. Since PAH occurred only in NREM sleep and correlated with arousal increment, it may have the function of suppressing NREM sleep's cortical arousal. PAH was relatively common in healthy young participants. Since PAH occurred in a state

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Nonalcoholic fatty liver disease (NAFLD) is an inflammatory lipotoxic disorder with a prevalence of over 25% worldwide. However, safe and effective therapeutic agents for the management of NAFLD are still lacking. We aimed to investigate the hepatoprotective effect and molecular mechanism of 4-acetylantroquinonol B (4-AAQ, a natural ubiquinone derivative obtained from the mycelia of Antrodia cinnamomea. RAW264.7 and J774A.1 cells were treated with 4-AAQB and then stimulated with LPS or tunicamycin (TM) for 24h. Inflammatory responses,