https://www.selleckchem.com/pr....oducts/adaptaquin.ht
Background Chemoresistance is a major obstacle to improving the survival rate of colorectal cancer (CRC) patients. Forkhead box protein C2 (FOXC2), a member of the forkhead box (Fox) transcription factor family, is reported to be an important regulator of epithelial-to-mesenchymal transition (EMT) and plays a key role in tumor progression. However, little is known about the effects of FOXC2 on oxaliplatin (OXA) resistance in CRC. Methods OXA-resistant cells were generated from HCT116 cells. CCK-8, colony formation, flow cytometry and
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