https://www.selleckchem.com/pr....oducts/Flavopiridol.
Although the phosphorylation of 4E-BP1 that has been detected in high-grade prostate cancer has been reported in previous studies, overexpression of p4E-BP1 and 4EBP1 and their clinical significance in prostate cancer still remain unknown. One hundred sixsamples of prostate tissues were collected and analyzed by immunohistochemistry with p4E-BP1 or 4E-BP1specific antibodies. Everolimus was used to block the phosphorylation of p4E-BP1, and then flow cytometry, clone formation, transwell, and wound healing assays were performed to de