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To analyze the nursing diagnosis NANDA-I - Caregiver Role Strain validation studies. Integrative literature review. Research of studies carried out between 2000 and 2018 with the descriptors caregivers, nursing diagnosis and validation study in the following databases Web of Science, EBESCOhost, Scielo Brasil and Portugal, LILACS, RCAAP, CAPES, NANDA-I website, and in the bibliographic references of the articles. Articles in Portuguese, English or Spanish were included. The sample consisted of seven validation studies, with heterogeneity