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nts undergoing transplantation, including those recently introduced in our therapeutic arsenal. To describe the development of the Antidotos_bot chatbottool, which is used to facilitate the search for information in the AntidoteAdministration Guide and to perform useful calculations in the use of antidotes. In January 2019, we proposed developing a freely accessiblechatbot on Telegram® using Xenioo®. Software development defined theway it interacts with users and incorporated calculation functionalities.Internal validation was conducted