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ADHD Treatment Medication Many people with ADHD are able to benefit from medication to improve their abilities of control and concentration. These medicines are called stimulants. They affect the brain chemical dopamine and norepinephrine. Atomoxetine and guanfacine are non-stimulant drugs that also aid in the treatment of ADHD. Treatment can consist of psychotherapy, medication or a combination of both. Behavioral therapy is most effective when started immediately after the diagnosis is established. Stimulants Stimulants increase the levels of brai