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sions is required to achieve very good results. Acne scar is a distressing psychosocial problem, and it has a negative effect on the quality of life. Although variety of approaches are available, demand of less invasive and more effective ways for their treatment is needed. This study aimed to assess and compare the clinical safety, efficacy, and tolerability of fractional carbon dioxide (FCO ) laser versus fractional microneedling radio frequency (MNRF) in the management of acne scars. This study was a prospective, observational, nonra