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ADHD in Adults - Treatment Options ADHD is a common neurobiological disorder that affects 4.4 percent of the population. It is associated with a high rate of comorbidity, such as anxiety, depression, and substance abuse, and significant social, emotional and occupational impairments. Both psychotherapy and medication are effective treatments for adults suffering from ADHD. Stimulants such as methylphenidate and amphetamine are the most frequently prescribed drugs. Medications Many adults with ADHD experience significant improvemen