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Patients with better cartilage had higher WOMAC pain improvement when their particular baseline scores had been worse, whereas the trend was reversed for patients with cartilage reduction at standard. Intra-articular use of APS for moderate to moderate knee OA ended up being safe, and considerable discomfort enhancement ended up being reported 36 months after just one shot. Customers with much better cartilage status seem to respond much better than patients with increased carti