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Acidosis and higher lactate predict worse outcomes in cardiogenic shock (CS) patients. We sought to determine whether overall acidosis severity on admission predicted in-hospital mortality in CS patients. This retrospective descriptive analysis included CS patients admitted to a single academic tertiary cardiac intensive care unit from 2007 to 2015. Admission arterial pH, base excess and anion gap values were used to generate a Composite Acidosis Score (range 0 to 5, with a score ≥2 defining Severe Acidosis). Adjusted in-hospital mortal