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Elite controllers (ECs) are people living with HIV who spontaneously control viral replication without antiretroviral therapy. We observed that elevated anti-CMV IgG levels correlated with annual CD4 T-cell count decay in ECs independently of age, sex and HLA type. Elevated anti-CMV titers may favor disease progression in ECs. The aim of this evidence-based theoretically informed article was to provide an overview of how and why the COVID-19 outbreak is particularly detrimental for the health of older Black and Latinx adults. We draw u