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Forty-five (12.1%) patients experienced severe acute respiratory failure requiring respiratory support. Forty-seven (12.6%) patients died. Those with worse outcomes were older (P=.002) and presented significantly higher NLR at admission (P=.001), greater increase in Peak NLR (P.001) and higher increasing speed of NLR (P=.003) compared with follow-up patients. In a multivariable logistic regression, age, cardiovascular disease and C-reactive protein at admission and Peak NLR were significantly associated with death. NLR is an easily