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In Houston, a total of 4808 cases were assessed. There was an initial drop of~30% in cases at the pandemic onset. Compared to 2019, there was a significant reduction in mild strokes (NIHSS 1-5) [N (%), 891 (43) vs 635 (4, P=0.02]. There were similar mean (SD) (mins) DTN [44 (17) vs 42 (17), P=0.14] but significantly prolonged DTG times [94 (15) vs 85 (2, P=0.005] in 2020. The COVID-19 pandemic led to a global reduction in stroke admissions and treatment interventions and prolonged treatment time metrics. The COVID-19 pandemic led to
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