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Somatic and visceral nociception dimensions and sedation results had been compared among remedies and with time. Sedation, visceral antinociception, and somatic antinociception effects of M20V400 and M40V800 had been reviewed for noninferiority to outcomes of M20, and plasma drug focus information were evaluated for equivalence between treatments. RESULTS Plasma dexmedetomidine concentrations after administration of M20 and M40V800 had been equivalent. Sedation scores, visceral nociception dimensi