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Treatment For ADHD The main treatments for adding are medication and psychosocial therapy (psychotherapy). The drugs include stimulants like methylphenidate, amphetamine and atomoxetine. They may also be non-stimulants, such as clonidine and Guanfacine. should not be used by patients who have active substance abuse problems but they can be considered in those who are in stable recovery. Combination treatment with antidepressants (particularly SSRIs) is also an option. Stimulants Stimulants boost dopamine and norepinephrine l