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Introduction Anxiety and depression are significant concerns in breast cancer patients, and it may remain for a long term after primary treatments. The hospital anxiety and depression scale (HADS) is widely used to measure depressive and anxiety symptoms in clinical practices. The purpose of this study was to assess the psychometric properties of the Persian version of this scale in Iranian breast cancer survivors. Methods A total of 305 patients with breast cancer, refered to Cancer Hospital in northen Iran and completed the primary

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Histopathological changes seen in murine hypopharyngeal mucosa confronted with acidic bile had been preceded because of the overexpression of Tnf, Il6, Bcl2, Egfr, Rela, Stat3, additionally the deregulation of miR-21, miR-155, miR-192, miR-34a, miR-375, and miR-451a. This is the very first research to document that acidic bile is carcinogenic in the upper aerodigestive region. We indicated that oxidative DNA-damage produced by acidic bile in conjunction with NF-κB-related anti