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Convertible Cribs Unlike traditional cribs, convertible ones end up being complete youth bedrooms. Depending on the model you pick, it can become a cot and a 90x200cm bed for a brother or sister, friend or unexpected visitor to oversleep. Besides being flexible, they are also inexpensive. They assist you avoid investing cash on several beds as your kid grows, making them a smart choice for your growing family. They are easy to asse

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Adrenocortical carcinoma (ACC) presents a high risk of relapse and metastases with outcomes not improving despite extensive research and new targeted therapies. We recently showed that the Hedgehog receptor Patched is expressed in ACC, where it strongly contributes to doxorubicin efflux and treatment resistance. Here, we report the identification of a new inhibitor of Patched drug efflux, the anti-histaminergic drug astemizole. We show that astemizole enhances the cytotoxic, proapoptotic, antiproliferative and anticlonogenic effects of