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021), poor 5-year OS (HR = 0.375; 95% CI 0.232-0.606; p 0.00, DSS (HR = 0.374; 95% CI 0.235-0.595; p 0.00, and DFS (HR = 0.454; 95% CI0.254-0.813; p = 0.008). T3-4 stage, N2-3 stage and poor differentiation are independent risk factors for LVI of HPSCC; LVI increases the local recurrence and regional recurrence rate, and decreases 5-year OS, DFS and DSS of HPSCC. T3-4 stage, N2-3 stage and poor differentiation are independent risk factors for LVI of HPSCC; LVI increases the local recurrence and regional recurrence rate, and
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