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0 mg/kg in rats, respectively. The absolute oral bioavailability of XPP was 4.6%. This article is protected by copyright. All rights reserved.BACKGROUND AND OBJECTIVES The aim of this study is to assess the survival, function, radiographic appearance, and modes of failure of extracorporeal irradiated (ECI) autografts in a long-term setting. METHODS We retrospectively reviewed 87 patients who were treated for bone and soft tissue tumors using ECI autografts between 1988 and 2009. RESULTS The 56 patients had a minimum follow-up of 10